Polyps can be on one or both of the vocal folds. They may look like a bump, a blister, or a thin, long growth. Most polyps are bigger than nodules. You may hear them called "polypoid degeneration" or "Reinke’s edema." To differentiate between a nodule and a polyp, think of a nodule as a callous and a polyp as a blister.
Polyps tend to cause vocal instability and a hoarse, rough, voice quality. Vocal fatigue is often felt and they make the voice very unpredictable. Polyps can be surgically removed if improvement is not seen with voice therapy. Voice therapy is typically recommended following surgical removal to retrain the voice using healthy vocal habits.